Older


Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation
Yamamoto S, Watanabe Y, van der Spek PJ, Watanabe T, Fujimoto H, Hanaoka F, Ohkuma Y.
Mol Cell Biol. 2001 Jan;21(1):1-15.
http://mcb.asm.org/content/21/1/1.long

Characterization of a novel human cell-cycle-regulated homologue of Drosophila dlg1
Bassal S, Nomura N, Venter D, Brand K, McKay MJ, van der Spek PJ.
Genomics. 2001 Sep;77(1-2):5-7.
http://www.sciencedirect.com/science/article/pii/S088875430196570X

The three subfamilies of leucine-rich repeat containing G protein-coupled receptors (LGR): Identification of LGR6 and LGR7 and the signaling mechanism for LGR7
Sheau Yu Hsu, Masataka Kudo, Thomas Chen, Koji Nakabayashi, Alka Bhalla, Peter J. van der Spek, Marcel van Duin, and Aaron Hsueh
Molecular Endocrinology August 2000, p 1257-1271.
http://mend.endojournals.org/content/14/8/1257.long

Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans.
Parisi S, McKay MJ, Molnar M, Thompson MA, van der Spek PJ, van Drunen-Schoenmaker E, Kanaar R, Lehmann E, Hoeijmakers JH, Kohli J.
Mol. Cell. Biol. 19(5): 3515-28, 1999.
http://mcb.asm.org/content/19/5/3515.long

A novel anion transporter gene is mutated in sialic acid storage diseases
Frans W. Verheijen, Elly Verbeek, Nina Aula, Cecile E. M.T. Beerens, Adrie C. Havelaar, Marijke Joosse, Leena Peltonen, Pertti Aula, Hans Galjaard, Peter J. van der Spek and Grazia M. S. Mancini.
Nature Genetics 23: 462-465, 1999.
http://www.nature.com/ng/journal/v23/n4/full/ng1299_462.html

Identification of BCAR3 by random search for genes involved in antiestrogen resistance of human breast cancer cells
Ton van Agthoven, Thecla L.A. van Agthoven, Anita Dekker, Peter J. van der Spek, Lilian Vreede and Lambert C.J. Dorssers
EMBO Journal 17(10) 2799-2808, 1998.
http://www.nature.com/emboj/journal/v17/n10/full/7590987a.html

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair
Kaoru Sugasawa, Jessica M.Y. Ng, Chikahide Masuitani, Shigenori Iwai, Peter J. van der Spek, Andre P.M. Eker, and Jan H.J. Hoeijmakers
Molecular Cell 2: 223-232, 1998
http://www.sciencedirect.com/science/article/pii/S109727650080132X

SMT3A, a human homologue of the S.cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family
Vincenza Lapenta, Pietro Chiurazzi, Peter J. van der Spek, Antonio Pizzuti, Fumio Hanaoka, and Christina Brahe
Genomics 40: 362-366, 1997.
http://www.sciencedirect.com/science/article/pii/S0888754396945565

Mammalian nucleotide excision repair and syndromes
W. Vermeulen, J. de Boer, E. Citterio, A.J. van Gool, G.T.J. van der Horst, N.G.J. Jaspers, W.L. de Laat, A.M. Sijbers, P.J. van der Spek, K. Sugasawa, G. Weeda, G.S. Winkler, D. Bootsma, J.-M. Egly and J.H.J. Hoeijmakers
DNA Damage and Mutagenesis 25: 309-315, 1997.

Identification and characterization of XPC-binding domain of hHR23B
Chikahide Masutani, Marito Araki, Kaoru Sugasawa, Peter J. van der Spek, Ayumi Yamada, Akio Uchida, Takafumi Maekawa, Dirk Bootsma, Jan H.J. Hoeijmakers, and Fumio Hanaoka
Mol. Cell. Biol. 17(12): 6915-6923, 1997.
http://mcb.asm.org/content/17/12/6915.long

Two human homologs of RAD23 are functionally interchangable in complex formation and stimulation of XPC repair activity
Kaoru Sugasawa, Jessica M.Y. NG, Chikahide Masuitani, Takafumi Maekawa, Akio Uchida, Peter J. van der Spek, André Eker, Suzanne Rademakers, Cécile Visser, Abdelilah Aboussekhra, Richard D. Wood, Fumio Hanaoka, Dirk Bootsma and Jan H.J. Hoeijmakers
Mol. Cell. Biol. 17(12): 6924-6931, 1997.
http://mcb.asm.org/content/17/12/6924.long

Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23
Peter J. van der Spek, Cécile E. Visser, Fumio Hanaoka, Bep Smit, Anne Hagemeijer, Dirk Bootsma, and Jan H.J. Hoeijmakers
Genomics 31, 20-27, 1996
http://www.sciencedirect.com/science/article/pii/S088875439690004X

HHR23B, a human Rad3 homolog, stimulates XPC protein in a nucleotide excision repair in vitro
Kaoru Sugasawa, Chikahide Masutani, Akio Uchida, Takefumi Maekawa, Peter J. van der Spek, Dirk Bootsma, Jan Hoeijmakers, and Fumio Hanaoka
Mol. Cell. Biol. 16(9):4852-4861, 1996.
http://mcb.asm.org/content/16/9/4852.long

XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes
Peter J. van der Spek, Andre Eker, Suzanne Rademakers, Cécile Visser, Kaoru Sugasawa, Chikahide Masutani, Fumio Hanaoka, Dirk Bootsma, and Jan Hoeijmakers
Nucl. Acids Res. 24(13) 2551-2559, 1996.
http://nar.oxfordjournals.org/content/24/13/2551.long

Conference report: 10th International Congress of Radiation Research, Würzburg, Germany, August 27-September 1, 1995
Michael J. McKay, Peter van der Spek, Henk Roest, Dirk Bootsma
Mutation Research 363: 137-146, 1996

Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse
Michael J. McKay, Christine Troelstra, Peter J. van der Spek, Roland Kanaar, Bep Smit, Anne Hagemeijer, Dirk Bootsma, and Jan H.J. Hoeijmakers
Genomics 36: 305-315, 1996
http://www.sciencedirect.com/science/article/pii/S0888754396904668

Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors
P.J. van der Spek, K. Kobayashi, D. Bootsma, M. Takao, A.P.M. Eker, and A. Yasui
Genomics 37: 177-182, 1996
http://www.sciencedirect.com/science/article/pii/S088875439690539X

Mutational analysis of the human nucleotide excision repair gene ERCC1
Anneke M. Sijbers, Peter J. van der Spek, Hanny Odijk, Joke van den Berg, Marcel van Duin, Andries Westerveld, Nicolaas G.J. Jaspers, Dirk Bootsma and Jan H.J. Hoeijmakers
Nucleic Acids Research 24(17): 3370-3380, 1996
http://nar.oxfordjournals.org/content/24/17/3370.long

Nucleotide excision repair syndromes: molecular basis and clinical symptoms
Dirk Bootsma, Geert Weeda, Wim Vermeulen, Hanneke van Vuuren, Christine Troelstra, Peter J. van der Spek and Jan Hoeijmakers
Phil. Trans. R. Soc. Lond. B. 347, 75-81, 1995
http://rstb.royalsocietypublishing.org/content/347/1319/75.long

Involvement of a spliced and defective human foamy virus in the establishment of chronic infection
Ali Saïb, Marcel Koken, Peter van der Spek, Jorge Périès, and Hugues de Thé
Journal of Virology 69(9) 5261-5268, 1995
http://jvi.asm.org/content/69/9/5261.long

Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23
Chikahide Masutani, Kaoru Sugasawa, Junn Yanagisawa, Tadao Sonoyama, Michio Ui, Takemi Enemoto, Koji Takio, Kiyoji Tanaka, Peter J. van der Spek, Dirk Bootsma, Jan Hoeijmakers and Fumio Hanaoka
EMBO Journal 13(8) 1831-1843, 1994
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC395023/?tool=pubmed

Chromosomal localization of three repair genes: The xeroderma pigmentosum group C gene and two human homologs of yeast RAD23
P. J. van der Spek, E.M.E. Smit, H.B. Beverloo, K. Sugasawa, C. Masutani, F. Hanaoka, J.H.J. Hoeijmakers, and A. Hagemeijer
Genomics 23, 651-658, 1994
http://www.sciencedirect.com/science/article/pii/S0888754384715540
 

Dr. Molewaterplein 50, Suite Ee-1540, 3015 GE Rotterdam. The Netherlands, Europe. Phone: +31 (0)10 70 43 491. Fax: +31 (0)10 70 44 161. E-mail: bioinformatics@erasmusmc.nl